Esomeprazole is often a CYP2C19 inhibitor. When starting off or ending cure with esomeprazole, the opportunity for interactions with drugs metabolised through CYP2C19 should be thought of.
Distinctive populations Renal impairment Dose adjustment isn't necessary in clients with impaired renal function. Because of constrained working experience in individuals with extreme renal insufficiency, these patients ought to be addressed with warning (see section 5.2).
Inconsistent facts about the medical implications of a PK/PD interaction of esomeprazole with regards to significant cardiovascular events are described from equally observational and clinical research. As being a precaution, concomitant usage of clopidogrel really should be discouraged.
NgÆ°á»i dùng nên cân nhắc liá»u lượng đặc biệt: Äối vá»›i những ngÆ°á»i có vấn Ä‘á» vá» gan nghiêm trá»ng thì liá»u tối Ä‘a của Esomeprazole không hÆ¡n 20 mg má»—i ngà y.
Concomitant remedy with omeprazole (twenty mg daily) and digoxin in healthier topics increased the bioavailability of digoxin by 10 % (up to 30 % in two away from 10 subjects). Digoxin toxicity is seldom reported. Even so, warning need to be exercised when esomeprazole is offered at high doses in elderly sufferers. Therapeutic drug checking of digoxin should really then be reinforced.
Liá»u dùng thông thÆ°á»ng cho trẻ em mắc bệnh ăn mòn dạ dà y do GERD qua trung gian axit
Subacute cutaneous lupus erythematosus (SCLE) Proton pump inhibitors are connected with quite infrequent circumstances of SCLE. If lesions manifest, specifically in Sunshine-exposed areas of the skin, and when accompanied by arthralgia, the patient should really request professional medical assistance instantly along with the wellbeing care Skilled thuoc tang cuong suc khoe ought to consider halting Esomeprazole.
Ung thÆ° vúUng thÆ° phổiUng thÆ° đại trá»±c trà ngUng thÆ° dạ dà yUng thÆ° cổ tá» cungUng thÆ° tuyến tiá»n liệtUng thÆ° ganUng thÆ° daUng thÆ° xÆ°Æ¡ngUng thÆ° bà ng quangUng thÆ° tuyến giápUng thÆ° buồng trứngUng thÆ° máuUng thÆ° tuyến tụyU nãoCác bệnh ung thÆ° khácU lymphoUng thÆ° đầu cổ
Trong trÆ°á»ng hợp khẩn cấp, gá»i ngay cho Trung tâm cấp cứu a hundred and fifteen hoặc đến trạm Y tế địa phÆ°Æ¡ng gần nhất.
Liá»u dùng thông thÆ°á»ng cho trẻ em mắc bệnh trà o ngược dạ dà y thá»±c quản và ăn mòn thá»±c quản:
Tình trạng sức khá»e của bạn có thể ảnh hưởng đến việc sá» dụng thuốc nà y. Báo cho bác sÄ© biết nếu bạn có bất kỳ vấn Ä‘á» sức khá»e nà o, đặc biệt là :
Results of esomeprazole to the pharmacokinetics of other prescription drugs Protease inhibitors Omeprazole continues to be documented to communicate with some protease inhibitors. The scientific great importance as well as the mechanisms driving these documented interactions are usually not always recognized. Improved gastric pH for the duration of omeprazole procedure may alter the absorption of your protease inhibitors. Other possible interaction mechanisms are via inhibition of CYP 2C19. For atazanavir and nelfinavir, thuoc tang cuong suc khoe decreased serum ranges happen to be noted when offered together with omeprazole and concomitant administration is just not recommended. Co-administration of omeprazole (40 mg once every day) with atazanavir 300 mg/ritonavir one hundred mg to healthful volunteers resulted in a substantial reduction thuoc tang cuong suc khoe in atazanavir exposure (roughly seventy five% minimize in AUC, Cmax and Cmin).
Liá»u dùng cho bệnh loét dạ dà y: 20mg hoặc 40mg uống má»™t lần má»—i ngà y trong tối Ä‘a six tháng.
Tiếp tục dùng thuốc cho đến hết thá»i gian Ä‘iá»u trị cho dù bạn có cảm thấy khá»e hÆ¡n. Báo cho bác sÄ© biết nếu bệnh tiếp tục kéo dà i hoặc trầm trá»ng hÆ¡n.